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As nicotine, the addictive chemical in tobacco, activates processes in parts of the brain that regulate and control many things, including mood and cognitive function, offering a safer alternative to smoking is essential to getting smokers off tobacco

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[5] It was also referenced in the Australian YouTube series The Big Lez Show, with character Mike Nolan saying that smoking a Marlboro Red is akin to "smoking a White Ox no filter, fuck that for a joke [6] ", referring to the traditional Australian way of smoking White Ox as a rolled cigarette without a filter (a part of the brand's inseparable association with prison life)